Investigations of Tll Suspensions

Thallous iodide suspensions were obtained by direct mixing of TlN03 and Na! solutions. The amount of TH was kept constant in the systems, while the concentrations of Na! (in excess), laurylamine nitrate (LAN) or myristylamine nitrate (MAN) were varied. Tyndallometric values were recorded as the function of Na!, LAN, and MAN concentrations respectively, for suspensions aged for various times. Particle sizes of differently aged TH in \u27Suspensions containing Na! and Eu(N03)a in solution were determined. Tyndal.:. lometry and electronmicroscopy showed fast particle growth of TH in suspension. After about 10 minutes the TH particle grew up to 1.3 μ. The zero point of charge, determined by microelectrophoresis, was attained at 0.001-0.005 M Na! and 0.0001-0.0005 M LAN depending on the conditions under which the system had been prepared. The results of radiometrically recorded adsorption- desorption equilibria show a constant increase of the adsorption capacity as the electrolyte concentration increases

Investigations of Tll Suspensions

Thallous iodide suspensions were obtained by direct mixing of TlN03 and Na! solutions. The amount of TH was kept constant in the systems, while the concentrations of Na! (in excess), laurylamine nitrate (LAN) or myristylamine nitrate (MAN) were varied. Tyndallometric values were recorded as the function of Na!, LAN, and MAN concentrations respectively, for suspensions aged for various times. Particle sizes of differently aged TH in \u27Suspensions containing Na! and Eu(N03)a in solution were determined. Tyndal.:. lometry and electronmicroscopy showed fast particle growth of TH in suspension. After about 10 minutes the TH particle grew up to 1.3 μ. The zero point of charge, determined by microelectrophoresis, was attained at 0.001-0.005 M Na! and 0.0001-0.0005 M LAN depending on the conditions under which the system had been prepared. The results of radiometrically recorded adsorption- desorption equilibria show a constant increase of the adsorption capacity as the electrolyte concentration increases

Determining the structure of a large tilted block between two major boundary faults in a continental rift (central Lake Baikal): a reflection seismic study

Between the major boundary faults of the central part of Lake Baikal (ie. the Ol’khon fault and the Primorsky fault), a structurally complex tilted area exists that is strongly influenced by the interaction between these two faults. This area, that is about 30 kilometer wide and a 100 kilometers long, consists of three main parts: Pri-Ol’khon, Ol’khon-island and the submerged Maloe More depression. It is believed that the area formed by the gradual propagation of the Primorsky fault in a southeast direction towards the Ol’khon fault.During the summer of 2001 a large amount of high resolution reflection seismic profiles were shot in Maloe More (>600 km), that could be used to get a better insight in the structural development of the area, and in the geometry of its different sub-blocks and basins. In a first stage we have investigated the morphology of the basement underneath the sedimentary cover, and we determined which structures were fault related and which not. Age constraints on the subsequent evolution came from the correlation of the sedimentary units in Maloe More with deposits on Ol’khon-island, and with data from the long BDP-cores in a nearby area (Academician Ridge).The depth of the basement gradually increases from the southwest towards the northeast, and its morphology is characterised by several ridge structures and faults that strike at high-angle to the main faults. Several of these ridges border basins that contain relatively old sediments (Miocene age; Unit A) later overlain by younger units. Therefore the main basement structures of the Maloe More area should be older than the general believed age for the southward propagation of the Primorsky fault (1 Ma according to earlier models). Moreover the occurrence of relatively thick deposits of unit A in the southwestern extremity of Maloe More and in Ol’khon-gate contradicts the idea that these parts of the area are the youngest, being submerged only recently.Instead, older (isolated) sedimentary traps and lacustrine environments must have existed in this area. Faulting in the younger sediments however shows that the presentday activity of the major boundary faults, still has a pronounced effect on the local structure between them. Some of the formed basins are still determined by displacements on the older structures.For this study we have tried to determine the evolution of the Maloe More area, based on its interpreted structure and the relation with overlying sedimentary deposits, and we have tried to link our observations with existing models for the development of the Primorsky and Ol’khon faults

Propagation of the Primorsky Fault in the central part of Lake Baikal and the evolution of Maloe More

The Primorsky Fault is one of the two major western boundary faults in the central part of Lake Baikal. According to the existing fault growth model (e.g. Agar and Klitgord, 1995), this fault has propagated gradually in a southward direction. During this propagation, the Primorsky Fault has cut through the footwall of the Ol’khon Fault, which is the other major boundary fault 35–40km to the south-east. This propagation has controlled the submergence of the Ol’khon Region which forms a large tilted block between both faults.Based on the interpretation of high-resolution reflection seismic profiles of the submerged part of the Ol’khon Region (ie. Maloe More), different depocentres have been identified in the hanging-wall region of the Primorsky Fault. These depocentres correspond to small basins that are separated from each other by distinct basement ridges, with an orientation that strikes almost perpendicularly to the Primorsky Fault. The occurrence of the oldest sedimentary deposits (Unit A, Miocene age) in depocentres in the southern part of Maloe More, indicates that old sedimentary traps and lacustrine environments must have existed in the area. This finding contradicts the existing growth model for the Primorsky Fault, which assumes that only a recent (ca. 1Ma) and gradual propagation of the fault is responsible for the increasing subsidence in Maloe More. In the different sub-basins, younger sediments (Unit B, Upper Pliocene) overlie the deposits of Unit A. Nevertheless, the upper parts of Unit B are also present on the different basement ridges. The thickness of Unit B is on the northeastern ridges in Maloe More considerably greater than on those more to the south-west, indicating that they have been submerged for a longer time. Careful investigation of a RESURS satellite image of the area has revealed a possible segmentation of the Primorsky Fault, with segment boundaries occurring at the location of the different basement ridges in Maloe More.We believe that the growth of the Primorsky Fault can therefore be described in two different stages. A first stage, during the deposition of Unit A, was characterised by the evolution of 5 different (isolated) segments that defined small basins in Maloe More. The observed basement ridges corresponded at that time to intrabasin highs that resulted from the displacement deficit between the different fault segments. Increasing extension lead to the further growth of the segments, causing a final linkage between them. This linkage marks the onset of a second stage, which was achieved during the deposition of Unit B. Linkage between fault segments caused a displacement increase (mainly at the former location of the segment boundaries), resulting in the submergence of the basement ridge. Seen the thicker deposits of Unit B on the northeastern ridges in Maloe More, we believe that the segment linkage was first established between the northernmost fault segments of the Primorsky Fault. Subsequent linkages between other segments more to the south, and the associated post-linkage displacement increases, caused the further submergence of Maloe More towards the southwest in later stages

Sandbox simulations of relay ramp evolution

The interaction between two offset overlapping normal faults is characterised by the presence of a relay ramp. In order to investigate the way these structures develop, sandbox experiments were carried out. To simulate the brittle crust, we used dry quartz sand that was extended by means of a rubber sheet located at its base.We imposed the initial configuration of the two interacting normal faults by placing silicone bars at the base of the sand-pack, above the rubber sheet. These, under extension, generated a velocity discontinuity responsible for the development of the normal faults, which later interacted and grew further within the sand package. By varying the initial configuration of the silicone bars, we could easily vary the spacing (distance) between the segments, their overlap, their length and their orientation, and test the influence of these parameters on the development of the ramp between the segments. The modeled faults had aspect ratio’s varying between 2.5 and 5.The relay structures in the experiments were characterised by birth, growth and decay. Birth of a relay ramp marked the onset of interaction and was inferred when a tilt of the sand surface could be observed between the two overlapping faults. Growth was characterised by the propagation of the two interacting faults, increasing the distance of overlap and the tilting of the sand layers. During this growth stage often the deflection of one of the fault traces could be observed. Decay occurred when the two initially isolated faults eventually got connected with each other and the ramp breached.A large part of the relay ramps that were formed in the models were breached — or were getting breached — before the final amount of extension was reached (ß ˜ 20%). For 55% of these ramps it was the hanging-wall fault that propagated towards the footwall fault, for 27% the footwall fault linked up with the hanging-wall fault, and for 18% of these breached ramps, a new fault developed that cross-cut the ramp. The new fault developed only in those cases where the original spacing of the faults was very small compared to their length. An experimental relation between the overlap and spacing of two segments was also determined and compared with earlier theoretical work.Finally, relay ramp evolution in the experiments was also characterised sometimes by several minor-order features which are not commonly observed in natural examples, such as: the further propagation of the fault tips after breaching, an increased displacement gradient just outside the relay ramp instead of inside, etc..

Atypical audiovisual speech integration in infants at risk for autism

The language difficulties often seen in individuals with autism might stem from an inability to integrate audiovisual information, a skill important for language development. We investigated whether 9-month-old siblings of older children with autism, who are at an increased risk of developing autism, are able to integrate audiovisual speech cues. We used an eye-tracker to record where infants looked when shown a screen displaying two faces of the same model, where one face is articulating/ba/and the other/ga/, with one face congruent with the syllable sound being presented simultaneously, the other face incongruent. This method was successful in showing that infants at low risk can integrate audiovisual speech: they looked for the same amount of time at the mouths in both the fusible visual/ga/− audio/ba/and the congruent visual/ba/− audio/ba/displays, indicating that the auditory and visual streams fuse into a McGurk-type of syllabic percept in the incongruent condition. It also showed that low-risk infants could perceive a mismatch between auditory and visual cues: they looked longer at the mouth in the mismatched, non-fusible visual/ba/− audio/ga/display compared with the congruent visual/ga/− audio/ga/display, demonstrating that they perceive an uncommon, and therefore interesting, speech-like percept when looking at the incongruent mouth (repeated ANOVA: displays x fusion/mismatch conditions interaction: F(1,16) = 17.153, p = 0.001). The looking behaviour of high-risk infants did not differ according to the type of display, suggesting difficulties in matching auditory and visual information (repeated ANOVA, displays x conditions interaction: F(1,25) = 0.09, p = 0.767), in contrast to low-risk infants (repeated ANOVA: displays x conditions x low/high-risk groups interaction: F(1,41) = 4.466, p = 0.041). In some cases this reduced ability might lead to the poor communication skills characteristic of autism

A genome-wide scan for common alleles affecting risk for autism

Although autism spectrum disorders (ASDs) have a substantial genetic basis, most of the known genetic risk has been traced to rare variants, principally copy number variants (CNVs). To identify common risk variation, the Autism Genome Project (AGP) Consortium genotyped 1558 rigorously defined ASD families for 1 million single-nucleotide polymorphisms (SNPs) and analyzed these SNP genotypes for association with ASD. In one of four primary association analyses, the association signal for marker rs4141463, located within MACROD2, crossed the genome-wide association significance threshold of P < 5 × 10−8. When a smaller replication sample was analyzed, the risk allele at rs4141463 was again over-transmitted; yet, consistent with the winner's curse, its effect size in the replication sample was much smaller; and, for the combined samples, the association signal barely fell below the P < 5 × 10−8 threshold. Exploratory analyses of phenotypic subtypes yielded no significant associations after correction for multiple testing. They did, however, yield strong signals within several genes, KIAA0564, PLD5, POU6F2, ST8SIA2 and TAF1C